diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 3df172e55..6b5e560b4 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -86,6 +86,7 @@ Interactive improvements
 - ``history`` and ``__fish_print_help`` now properly support ``less`` before version 530, including the version that ships with macOS. (:issue:`8157`).
 - ``help`` now knows which section is in which document again (:issue:`8245`).
 - fish's highlighter will now color options (starting with ``-`` or ``--``) with the color given in the new $fish_color_option, up to the first ``--``. It falls back on $fish_color_param, so nothing changes for existing setups (:issue:`8292`).
+- When executing a command, abbreviations are no longer expanded when the cursor is separated from the command by spaces, making it easier to suppress abbreviation expansion of commands without arguments. (:issue:`8423`).
 
 New or improved bindings
 ^^^^^^^^^^^^^^^^^^^^^^^^
diff --git a/src/reader.cpp b/src/reader.cpp
index 7145fc6c5..541341045 100644
--- a/src/reader.cpp
+++ b/src/reader.cpp
@@ -3325,7 +3325,7 @@ void reader_data_t::handle_readline_command(readline_cmd_t c, readline_loop_stat
             if (command_test_result == 0 || command_test_result == PARSER_TEST_INCOMPLETE) {
                 // This command is valid, but an abbreviation may make it invalid. If so, we
                 // will have to test again.
-                if (expand_abbreviation_as_necessary(1)) {
+                if (expand_abbreviation_as_necessary(0)) {
                     // Trigger syntax highlighting as we are likely about to execute this command.
                     this->super_highlight_me_plenty();
                     if (conf.syntax_check_ok) {
diff --git a/tests/checks/tmux-abbr.fish b/tests/checks/tmux-abbr.fish
new file mode 100644
index 000000000..c8af9fe51
--- /dev/null
+++ b/tests/checks/tmux-abbr.fish
@@ -0,0 +1,40 @@
+#RUN: %fish %s
+#REQUIRES: command -v tmux
+
+set -g isolated_tmux_fish_extra_args -C '
+    set -g fish_autosuggestion_enabled 0
+    function abbr-test
+    end
+    abbr -g abbr-test "abbr-test [expanded]"
+'
+isolated-tmux-start
+
+# Expand abbreviations on space.
+isolated-tmux send-keys abbr-test Space arg1 Enter
+tmux-sleep
+# CHECK: prompt {{\d+}}> abbr-test [expanded] arg1
+
+# Expand abbreviations at the cursor when executing.
+isolated-tmux send-keys abbr-test Enter
+tmux-sleep
+# CHECK: prompt {{\d+}}> abbr-test [expanded]
+
+# Use Control+Z right after abbreviation expansion, to keep going without expanding.
+isolated-tmux send-keys abbr-test Space C-z arg2 Enter
+tmux-sleep
+# CHECK: prompt {{\d+}}> abbr-test arg2
+
+# Or use Control+Space ("bind -k nul") to the same effect.
+isolated-tmux send-keys abbr-test C-Space arg3 Enter
+tmux-sleep
+# CHECK: prompt {{\d+}}> abbr-test arg3
+
+# Do not expand abbrevation if the cursor is not at the command, even if it's just white space.
+# This makes the behavior more consistent with the above two scenarios.
+isolated-tmux send-keys abbr-test C-Space Enter
+tmux-sleep
+# CHECK: prompt {{\d+}}> abbr-test
+
+# CHECK: prompt {{\d+}}>
+
+isolated-tmux capture-pane -p